Back to Builds

Poison Alchemist Build

S Tier
SilentEasy

Stack Poison early, then defend while passive damage carries the fight.

Playstyle

Stack Poison early, then defend while passive damage takes over the fight.

Win Condition

Apply enough Poison that enemies die without needing repeated attack pressure.

Pros

  • Reliable scaling damage
  • Safe against high-HP targets
  • Good at winning slow fights

Cons

  • Can be slow versus fast elites
  • Needs time to ramp
  • Artifact-style counters are awkward

Tags

poisonscalingcontrol

Video Tutorial

Silent Poison, My Easiest Wins So Far - Slay the Spire 2

Watch on YouTube